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Cas No. |
Product name |
1421373-62-7 |
Mutant EGFR inhibitor |
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Mutant EGFR inhibitor is a selective and potent Mutated EGFR inhibitor(L858R activating mutant, the Exonl9 deletion activating mutant and the T790M resistance mutant). |
1508250-71-2 |
EGF816 |
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EGF816 is a novel covalent inhibitor of mutant-selective EGFR; overcomes T790M-mediated resistance in NSCLC. |
497839-62-0 |
AEE788 (NVP-AEE788) |
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AEE788(NVP-AEE 788) is a potent inhibitor of EGFR and HER2/ErbB2 with IC50 of 2 nM and 6 nM, less potent to VEGFR2/KDR, c-Abl, c-Src, and Flt-1, does not inhibit Ins-R, IGF-1... |
194423-06-8 |
CL-387785 (EKI-785) |
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CL-387785(EKI785; WAY-EKI 785) is an irreversible inhibitor of EGFR with IC50 of 370+/-120 pM; is able to overcome resistance caused by the T790M mutation on a functional lev... |
1626387-80-1 |
AZD3759 |
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AZD3759 is a potent, oral active, CNS-penetrant EGFR inhibitor with IC50 of 0.3 nM, 0.2 nM, and 0.2 nM for EGFR (WT), EGFR (L858R), and EGFR (exon 19Del), respectively. |
882531-87-5 |
R1530 |
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R1530 multiple kinase inhibitor that has anti-angiogenic and anti-cancer activity. |
690206-97-4 |
ZM 306416 |
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ZM 306416 is a VEGFR (Flt and KDR) inhibitor for VEGFR1 with IC50 of 0.33 μM, but also found to inhibit EGFR with IC50 of <10 nM |
1050500-29-2 |
AST-1306 |
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AST-1306 is a novel irreversible inhibitor of EGFR and ErbB2 with IC50 of 0.5 nM and 3 nM, also effective in mutation EGFR T790M/L858R, more potent to ErbB2-overexpressing ce... |
1353550-13-6 |
Olmutinib |
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Olmutinib is an EGFR inhibitor. |
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