Tucidinostat ID:1593
| Synonyms: |
| CAS NO : 1616493-44-7 |
|
| Molecular Formula: C22H19FN4O2 |
| Molecular Weight: 390.4184 |
| Purity: 98% |
| Solubility: In DMSO |
| Storage: -20°C |
Availability and Price
| |
If the item is temporarily out of stock. Please email to sales@betterbiochem.com,we will inform you when we have it in stock. |
| In Stock |
| |
 Order |
Remarks:Tucidinostat (also known as HBI-8000, Chidamide, and CS-055) is a benzamide type inhibitor of histone deacetylase (HDAC) isoenzymes 1, 2, 3 and 10, with potential antineoplastic activity. Tucidinostat selectively binds to and inhibits HDAC leading to an increase of acetylation levels of histone protein H3. This agent also inhibits the expression of signaling kinases in the PI3K/Akt and MAPK/Ras signaling pathways and may result in cell cycle arrest and the induction of tumor cell apoptosis. This may inhibit tumor cell proliferation in susceptible tumor cells. HDACs, a class of enzymes that deacetylate chromatin histone proteins, are upregulated in many tumor types and play key roles in gene expression. Compared to some other benzamide type HDAC inhibitors, tucidinostat is more stable, more resistant to degradation and has a longer half-life.
Quality Control
H-NMR,C-NMR,LC-MS,HPLC. |
|
Related Products
 Others |
