AC-5216 ID:1514
Synonyms: |
CAS NO : 226954-04-7 |
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Molecular Formula: C23H23N5O2 |
Molecular Weight: 401.468 |
Purity: 98% |
Solubility: In DMSO |
Storage: -20°C |
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Remarks:Ligand of translocator protein (TSPO, peripheral benzodiazepine receptor). Exhibits high affinity for TSPO in rat whole brain (Ki = 0.297 nM), and high potency against human and rat glial TSPO (IC50 values are 2.73 and 3.04 nM respectively). Displays no noticeable binding to a number of other receptors, transporters or ion channels. XBD173;N-Ethyl-7,8-dihydro-7-methyl-8-oxo-2-phenyl-N-(phenylmethyl)-9H-purine-9-acetamide;Also displays anxiolytic and antidepressant effects in rodent models, without inducing benzodiazepine-like adverse effects.
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H-NMR,C-NMR,LC-MS,HPLC. |
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