Cas No. |
Product name |
808118-40-3 |
FG-4592 |
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FG-4592 is an HIF α prolyl hydroxylase inhibitor, stabilizes HIF-2 and induces EPO production. Phase 3. |
931398-72-0 |
IOX2 |
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IOX2 is a potent inhibitor of HIF-1α prolyl hydroxylase-2 (PHD2) with IC50 of 21 nM, >100-fold selectivity over JMJD2A, JMJD2C, JMJD2E, JMJD3, or the 2OG oxygenase FIH. |
1227158-85-1 |
BAY 87-2243 |
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BAY 87-2243 is a highly potent and selective inhibitor of hypoxia-induced HIF-1 activation. |
1154028-82-6 |
Molidustat (BAY85-3934) |
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Molidustat(BAY-85-3934) is a novel inhibitor of hypoxia-inducible factor (HIF) prolyl hydroxylase (PH) which stimulates erythropoietin (EPO) production and the formation of r... |
223387-75-5 |
FG-2216 |
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FG-2216 is a potent HIF-prolyl hydroxylase inhibitor with IC50 of 3.9 uM for PDH2 enzyme; orally bioavailable and induced significant and reversible Epo induction in vivo. |
1193383-09-3 |
JNJ-42041935 |
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JNJ-42041935 HIF-PHDs efficient selective inhibitors, pKi 7.3-7.9. |
960539-70-2 |
Daprodustat (GSK1278863) |
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Daprodustat (GSK1278863) is an orally administered hypoxia-inducible factor-prolyl hydroxylase (HIF-PH) inhibitor. |