Cas No. |
Product name |
1012054-59-9 |
CUDC-101 |
more... |
CUDC-101 is a potent multi-targeted inhibitor against HDAC, EGFR and HER2 with IC50 of 4.4 nM, 2.4 nM, and 15.7 nM, and inhibits class I/II HDACs, but not class III, Sir-type... |
1339928-25-4 |
CUDC-907 |
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CUDC-907 is a dual PI3K and HDAC inhibitor for PI3Kα and HDAC1/2/3/10 with IC50 of 19 nM and 1.7 nM/5 nM/1.8 nM/2.8 nM, respectively. Phase 1. |
404950-80-7 |
Panobinostat (LBH589) |
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Panobinostat (LBH589) is a novel broad-spectrum HDAC inhibitor with IC50 of 5 nM. Phase 3. |
287383-59-9 |
Scriptaid |
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Scriptaid is an inhibitor of HDAC. It shows a greater effect on acetylated H4 than H3. |
1396841-57-8 |
RGFP966 |
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RGFP966 is an HDAC3 inhibitor with IC50 of 0.08 μM, exhibits > 200-fold selectivity over other HDAC. |
852475-26-4 |
MC1568 |
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MC1568 is a selective HDAC inhibitor for maize HD1-A with IC50 of 100 nM. It is 34-fold more selective for HD1-A than HD1-B. |
783355-60-2 |
PCI-24781 |
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PCI-24781 (Abexinostat) is a novel pan-HDAC inhibitor mostly targeting HDAC1 with Ki of 7 nM, modest potent to HDACs 2, 3, 6, and 10 and greater than 40-fold selectivity agai... |
1228960-69-7 |
MLN0905 |
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MLN0905 is a potent inhibitor of PLK1 with IC50 of 2 nM. |
209783-80-2 |
Entinostat (MS-275, SNDX-275) |
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Entinostat (MS-275) strongly inhibits HDAC1 and HDAC3 with IC50 of 0.51 μM and 1.7 μM, compared with HDACs 4, 6, 8, and 10. Phase 3. |
1225497-78-8 |
Rigosertib (ON-01910) |
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Rigosertib (ON-01910) is a non-ATP-competitive inhibitor of PLK1 with IC50 of 9 nM. It shows 30-fold greater selectivity against Plk2 and no activity to Plk3. Phase 3. |