BAN ORL 24 ID:1554
| Synonyms: |
| CAS NO : 475150-69-7 |
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| Molecular Formula: C27H35N3O2.2HCl |
| Molecular Weight: 506.51 |
| Purity: 98% |
| Solubility: In DMSO |
| Storage: -20°C |
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Remarks:BAN ORL 24 is a potent and selective NOP (also known as KOR-3) receptor antagonist (IC50 values are 0.27, 2500, 6700 and > 10000 nM for NOP, κ-, μ- and δ-receptors respectively). BAN ORL 24 Inhibits nociceptin-induced stimulation of [35S]-GTPγS binding and Ca2+ mobilization in CHO cells in vitro and antagonizes NOP agonist-induced reduction in locomotor activity in vivo.BAN ORL 24 can is also a brain penetrant.
Quality Control
H-NMR,C-NMR,LC-MS,HPLC. |
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