Apilimod free base ID:1535
| Synonyms: |
| CAS NO : 541550-19-0 |
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| Molecular Formula: C23H26N6O2 |
| Molecular Weight: 418.501 |
| Purity: 98% |
| Solubility: In DMSO |
| Storage: -20°C |
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Remarks:Apilimod, also known as STA-5326, is a IL-12/IL-23 inhibitor. Apilimod inhibits IL-12 and IL-23 production - cytokines that are involved in autoimmune diseases - through the prevention of nuclear translocation of c-Rel. Synta Pharmaceuticals Corp is developing apilimod for the potential treatment of Crohn's disease (CD) and other autoimmune diseases. Preclinical studies demonstrated the successful inhibition of IL-12 and IL-23 production by the drug.
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H-NMR,C-NMR,LC-MS,HPLC |
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