AG 13958 ID:1525
| Synonyms: |
| CAS NO : 319460-94-1 |
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| Molecular Formula: C26H22FN7O |
| Molecular Weight: 467.4976 |
| Purity: 98% |
| Solubility: In DMSO |
| Storage: -20°C |
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Remarks:SU5402 is a multiple target inhibitor of VEGFR2 (Flk-1/KDR) and FGFR1 (IC50 at 20 and 30 nM,respectively). This agent inhibits PDGFRβ and EGFR with IC50 values of 510 nM and > 100 μM, respectively. [1]SU 5402 inhibits tyrosine phosphorylation of VEGFR2 and PDGFR in NIH 3T3 cells with IC50 values of 0.4 and 60.9 μM, respectively. This agent inhibits embryonic left-right determination and exhibits potent anticancer activity in vitro and in vivo.
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H-NMR,C-NMR,LC-MS,HPLC. |
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