Cas No. |
Product name |
847499-27-8 |
CEP-18770 (Delanzomib) |
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CEP-18770 is an orally active inhibitor of the chymotrypsin-like activity of proteasome with IC50 of 3.8 nM, with only marginal inhibition of the tryptic and peptidylglutamyl... |
659730-32-2 |
AMG517 |
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AMG 517 is a potent and selective TRPV1 antagonist, antagonizes capsaicin, proton, and heat activation of TRPV1 with IC50 of 0.76 nM, 0.62 nM and 1.3 nM |
1035270-39-3 |
AZD4547 |
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AZD4547 is a novel selective FGFR inhibitor targeting FGFR1/2/3 with IC50 of 0.2 nM/2.5 nM/1.8 nM, weaker activity against FGFR4, VEGFR2(KDR), and little activity observed ag... |
177355-84-9 |
DBeq |
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DBeQ is a selective, potent, reversible, and ATP-competitive p97 inhibitor with IC50 of 1.5 μM |
873697-71-3 |
Omecamtiv mecarbil(CK1827452) |
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Omecamtiv mecarbil (CK-1827452) is a specific cardiac myosin activator and a clinical drug for left ventricular systolic heart failure. Phase 2 |
1380432-32-5 |
Ehop-016 |
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EHop-016 is a specific Rac GTPase inhibitor with IC50 of 1.1 μM for Rac1, equally potent inhibition for Rac3 |
1333151-73-7 |
KPT185 |
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KPT-185 is a selective CRM1 inhibitor |
847591-62-2 |
ICG001 |
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ICG-001 antagonizes Wnt/β-catenin/TCF-mediated transcription and specifically binds to element-binding protein (CBP) with IC50 of 3 μM, but is not the related transcriptional... |
761439-42-3 |
TAE684 (NVP-TAE684) |
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TAE684 is a potent and selective ALK inhibitor with IC50 of 3 nM, 100-fold more sensitive for ALK than InsR |
1262036-50-9 |
LY2886721 |
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LY2886721 is an BACE inhibitor used for the treatment of Alzheimer's Disease |