Linsitinib (OSI-906) ID:1656
| Synonyms: |
| CAS NO : 867160-71-2 |
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| Molecular Formula: C26H23N5O |
| Molecular Weight: 421.5 |
| Purity: 98% |
| Solubility: In DMSO |
| Storage: -20°C |
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Remarks: Linsitinib, also known as OSI-906, is a n orally bioavailable small molecule inhibitor of the insulin-like growth factor 1 receptor (IGF-1R) with potential antineoplastic activity. OSI-906 selectively inhibits IGF-1R, which may result in the inhibition of tumor cell proliferation and the induction of tumor cell apoptosis. Overexpressed in a variety of human cancers, IGFR-1 stimulates cell proliferation, enables oncogenic transformation, and suppresses apoptosis.
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H-NMR,C-NMR,LC-MS,HPLC. |
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