Encorafenib ID:1655
| Synonyms: |
| CAS NO : 1269440-17-6 |
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| Molecular Formula: C22H27ClFN7O4S |
| Molecular Weight: 540.01 |
| Purity: 98% |
| Solubility: In DMSO |
| Storage: -20°C |
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Remarks: Encorafenib, also known as LGX-818, is an orally available Raf kinase inhibitor with potential antineoplastic activity. LGX818 specifically inhibits Raf kinase, a serine/threonine enzyme in the RAF/mitogen-activated protein kinase kinase (MEK)/extracellular signal-related kinase (ERK) signaling pathway. By inhibiting the activation of the RAF/MEK/ERK signaling pathway, the administration of LGX818 may result in a decrease in proliferation of tumor cells. The Raf mutation BRAF V600E is frequently upregulated in a variety of human tumors and results in the constitutive activation of the RAF/MEK/ERK signaling pathway that regulates cellular proliferation and survival. Check for active clinical trials or closed clinical trials using this agent.
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H-NMR,C-NMR,LC-MS,HPLC. |
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