Azeliragon ID:1552
Synonyms: |
CAS NO : 603148-36-3 |
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Molecular Formula: C32H38ClN3O2 |
Molecular Weight: 532.125 |
Purity: 98% |
Solubility: In DMSO |
Storage: -20°C |
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Remarks:Azeliragon, also known as TTP488 and PF-04494700, is a potent and orally active RAGE inhibitor. RAGE (receptor for advanced glycation endproducts) is a pattern recognition receptor, which affects the movement of amyloid, an Alzheimer's-associated protein, into the brain. In preclinical studies, azeliragon decreased brain amyloid in mice and improved their performance on behavior tests. Azeliragon is a promising agent for for Alzheimer's disease and cerebral amyloid angiopathy.
Quality Control
H-NMR,C-NMR,LC-MS,HPLC. |
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