A 769662 ID:1509
| Synonyms: |
| CAS NO : 844499-71-4 |
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| Molecular Formula: C20H12N2O3S |
| Molecular Weight: 360.38588 |
| Purity: 98% |
| Solubility: In DMSO |
| Storage: -20°C |
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Remarks:
6,7-Dihydro-4-hydroxy-3-(2'-hydroxy[1,1'-biphenyl]-4-yl)-6-oxo-thieno[2,3-b]pyridine-5-carbonitrile
Potent, reversible AMP-activated protein kinase (AMPK) activator (EC50 = 0.8 μM) that displays selectivity towards β1 subunit-containing heterotrimers. Inhibits fatty acid synthesis (IC50 = 3.2 μM) and decreases plasma glucose and triglyceride levels in vivo. Also inhibits proliferation of mesenchymal stem cells, and impedes reprogramming of mouse embryonic fibroblasts to iPSCs.
Quality Control
H-NMR,C-NMR,LC-MS,HPLC. |
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